International Journal of Web Applications Yan Hua Wang 9 2 2017 http://www.dline.info/ijwa/fulltext/v9n2/ijwav9n2_3.pdf Through the actual case of the implementation of the large state-owned oil enterprises, the chemical laboratory information management system construction, from the demand for research analysis is detailed. The system outline design, system detailed design, system testing and system operation maintenance, and several aspects elaborated the petroleum chemical industry information management systems methods and processes. This paper first analyzes the process characteristics of the operation and management of laboratory, research the internal staff demand, and explains the necessity of the construction of the system; secondly, combined with the laboratory, business needs and business situation, the study analyzed a set to conform to the laboratory work flow characteristics. Third, the laboratory information management system of the specific implementation plan is addressed. Then the analysis of the overall structure of the laboratory information management system, detailed design, specific design ideas and methods of database, sample testing process, management process, management reporting, data queries and other functional modules are studied. Finally, the paper summarizes and analyzes the advantages of the laboratory management information system in the practical application in petrochemical enterprises.