Journal of Information & Systems Management Xinzhi Zhuang 7 3 2017 http://www.dline.info/jism/fulltext/v7n3/jismv7n3_3.pdf With the rapid development of network technology, the B/S framework has been applied in many industries, such as hotel management system, air ticket reservation system and course selection system based on WEB. But the domestic medical colleges, but the lack of a mature application in nursing clinical practice in the field of information management system based on Web, even if there is in existence some defects, cannot fully integrate utilization of network resources. Based on the above issues, through and where the medical college teachers and students to fully communicate, a comprehensive analysis of them in daily nursing students’ clinical practice in the process of management demand, this paper using ASP technology for foundation design and implementation of a based on B / s medical college nursing clinical practice management system. There are three students in the use of wood management system to participate in the clinical practice of nursing students, internship hospital with the teacher as well as the administrator of the medical school. The main function modules include student information management, teacher or administrator announcement release, student achievement management, student information exchange platform, job management, internship identification table and internship records management, etc.. This article from the system requirements and analysis, design, detailed design and implementation of three parts to detail the entire process of system development. The system will present more mature of the application of network technology in a new field, reducing the human and material cost, improves the processing speed, realize the paperless office, and comprehensively improve the nursing professional teaching quality of clinical practice.